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The purpose of: this study was to elucidate the diagnostic yield of bronchoscopy for patients suspected for NTM: PD when sputum cannot reveal NTM. At the same time, we eval uated factors that affected the: results of bronchoscopy. Furthermore, we estimated the specificity of bronchoscopy for detecting: NTM.: Method: This: study utilized a retrospective cohort study design based on the review of medical records: and was conducted at St Luke’s International Hospital in Tokyo, Japan. Between January 1,: 2004 and June 30, 2018, among all adult patients who underwent bronchoscopy, two groups: were enrolled. Group A included all patients with nodular bronchiectasis pattern on chest: comp uted tomography ( findings who could not produce culture positive sputum for NTM: and therefore underwent bronchoscopy for the diagnoses of NTM PD. Group B comprised of: patients who received bronchoscopy suspected for lung cancer. Group A was used to eva luate: diagnostic yield of NTM PD using bronchoscopy, and group B was employed to measure: specificity of bronchoscopy.: Result: Diagnostic: yield of bronchoscopy for NTM PD was 114/205 ( 99 were patients of: pulmonary MAC, remainder were 10 patients of N TM other than MAC, and 5 patients oftuberculosis.: Logistic regression showed 4 factors associated with NTM PD: examination of the: upper lobe (odds ratio [ 2.31, 95% confidence interval [ 1.21 4.55), absence of: particular bacteria ( 3.35, 95% CI 1.44 8.30), absence of connective tissue disease (: 3.17, 95% CI: 1.25 8.79), and higher total CT scores ( 1.14, 95% CI: 1.03 1.27) Specificity: of bronchoscopy for NTM PD was 99.2% (900/: Conclusion: Bronchoscopy: showed moderate diagnostic yie ld and high specificity for NTM PD.", "subitem_description_type": "Abstract"}]}, "item_10006_dissertation_number_12": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "32633公修専第033"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "冨島, 裕"}, {"creatorName": "トミシマ, ユタカ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "4958", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tomishima, Yutaka", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "6612", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2021-09-15"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "MP[033]_abst.pdf", "filesize": [{"value": "313.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 313400.0, "url": {"label": "論文要旨", "url": "https://luke.repo.nii.ac.jp/record/2123/files/MP[033]_abst.pdf"}, "version_id": "5cfdea61-f0b3-45db-bd01-9162f7280658"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "nontuberculous mycobacterium", "subitem_subject_scheme": "Other"}, {"subitem_subject": "bronchoscope", "subitem_subject_scheme": "Other"}, {"subitem_subject": "specificity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "retrospective cohort", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium"}]}, "item_type_id": "10006", "owner": "4", "path": ["1", "17", "30", "217"], "permalink_uri": "http://hdl.handle.net/10285/13548", "pubdate": {"attribute_name": "公開日", "attribute_value": "2020-05-22"}, "publish_date": "2020-05-22", "publish_status": "0", "recid": "2123", "relation": {}, "relation_version_is_last": true, "title": ["Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium"], "weko_shared_id": -1}
Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium
http://hdl.handle.net/10285/13548
http://hdl.handle.net/10285/135482f0cee48-781c-4764-8fb7-50f4ef52ec9a
名前 / ファイル | ライセンス | アクション |
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論文要旨 (313.4 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2020-05-22 | |||||
タイトル | ||||||
タイトル | Diagnostic Yield of Bronchoscopy for Pulmonary Nontuberculous Mycobacterium | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | nontuberculous mycobacterium | |||||
キーワード | ||||||
主題 | bronchoscope | |||||
キーワード | ||||||
主題 | specificity | |||||
キーワード | ||||||
主題 | retrospective cohort | |||||
資源タイプ | ||||||
資源タイプ | thesis | |||||
著者 |
冨島, 裕
× 冨島, 裕× Tomishima, Yutaka |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: The: American Thoracic Society’s guideline of nontuberculous mycobacteria associated: pulmonary disease (NTM PD) suggests bronchoscopy as one of the ways to detect: nontuberculous mycobacterium ( However, the guideline also acknowledges that l imited: data are available on the utility of bronchoscope for the diagnosis of NTM PD. The purpose of: this study was to elucidate the diagnostic yield of bronchoscopy for patients suspected for NTM: PD when sputum cannot reveal NTM. At the same time, we eval uated factors that affected the: results of bronchoscopy. Furthermore, we estimated the specificity of bronchoscopy for detecting: NTM.: Method: This: study utilized a retrospective cohort study design based on the review of medical records: and was conducted at St Luke’s International Hospital in Tokyo, Japan. Between January 1,: 2004 and June 30, 2018, among all adult patients who underwent bronchoscopy, two groups: were enrolled. Group A included all patients with nodular bronchiectasis pattern on chest: comp uted tomography ( findings who could not produce culture positive sputum for NTM: and therefore underwent bronchoscopy for the diagnoses of NTM PD. Group B comprised of: patients who received bronchoscopy suspected for lung cancer. Group A was used to eva luate: diagnostic yield of NTM PD using bronchoscopy, and group B was employed to measure: specificity of bronchoscopy.: Result: Diagnostic: yield of bronchoscopy for NTM PD was 114/205 ( 99 were patients of: pulmonary MAC, remainder were 10 patients of N TM other than MAC, and 5 patients oftuberculosis.: Logistic regression showed 4 factors associated with NTM PD: examination of the: upper lobe (odds ratio [ 2.31, 95% confidence interval [ 1.21 4.55), absence of: particular bacteria ( 3.35, 95% CI 1.44 8.30), absence of connective tissue disease (: 3.17, 95% CI: 1.25 8.79), and higher total CT scores ( 1.14, 95% CI: 1.03 1.27) Specificity: of bronchoscopy for NTM PD was 99.2% (900/: Conclusion: Bronchoscopy: showed moderate diagnostic yie ld and high specificity for NTM PD. | |||||
学位名 | ||||||
学位名 | 修士(公衆衛生学) | |||||
学位授与機関 | ||||||
学位授与機関名 | 聖路加国際大学 | |||||
学位授与年度 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 2019 | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2020-03-10 | |||||
学位授与番号 | ||||||
学位授与番号 | 32633公修専第033 |