| Item type |
学位論文 / Thesis or Dissertation(1) |
| 公開日 |
2020-05-28 |
| タイトル |
|
|
タイトル |
The Effectiveness of a Cardioverter Defibrillator in Patients with Cardiac Amyloidosis: A systematic literature review |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
amyloidosis |
| キーワード |
|
|
主題 |
heart |
| キーワード |
|
|
主題 |
implantable cardioverter defibrillator |
| キーワード |
|
|
主題 |
ventricular tachycardia |
| キーワード |
|
|
主題 |
ventricular fibrillation |
| キーワード |
|
|
主題 |
sudden cardiac death |
| キーワード |
|
|
主題 |
systematic literature review |
| 資源タイプ |
|
|
資源タイプ |
thesis |
| その他（別言語等）のタイトル |
|
|
その他のタイトル |
心アミロイドーシス患者における植込み型除細動器の有効性: システマティックレビュー |
| 著者 |
時岡, 紗由理
Tokioka, Sayuri
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: Amyloidosis is a rare disease caused by tissue deposition of protein fibrils. In case of cardiac involvement, it is called cardiac amyloidosis (CA), which has a poor prognosis and causes sudden cardiac death (SCD). An implantable cardioverter defibrillator (ICD) prevents SCD due to ventricular tachyarrhythmia; however, ICD implantation in patients with CA is controversial because of the poor prognosis of CA and the possibility of pulseless electrical activity. This study is a systematic review aimed to evaluate the efficacy of ICD in patients with CA.: Methods: A systematic literature review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA). On June 30, 2019, a comprehensive literature search of Medline, PubMed, Embase, CINAHL and the Cochrane Library was performed. Longitudinal observational studies of patients with CA with implanted ICD were included. Primary outcomes were appropriate ICD therapy, all-cause mortality and one-year survival.: Results: Nine studies with a total of 704 CA patients with implanted ICD were included. The median incidence rate of appropriate ICD therapy was 26.0% (range 6.5-28.3%) of the patients during 21.5 (0-175) months of follow-up period. All-cause mortality was observed in 96 (41.3%) among 232 patients and median one-year survival was 79% (range 39-92%).: Conclusions: Patients with CA benefit from ICD implantation considering the incidence rate of appropriate ICD therapy and one-year survival. There is no evidence that ICD implantation can: 9: improve patients’ prognosis. Larger studies are needed to elucidate the impact of ICD on patients with CA and to develop selection criteria for implantation. |
| 学位名 |
|
|
学位名 |
修士(公衆衛生学) |
| 学位授与機関 |
|
|
|
学位授与機関名 |
聖路加国際大学 |
| 学位授与年度 |
|
|
内容記述 |
2019 |
| 学位授与年月日 |
|
|
学位授与年月日 |
2020-03-10 |
| 学位授与番号 |
|
|
学位授与番号 |
32633公修専第043 |
![MP[043]_abst.pdf](/static/images/icon/icon_16_pdf.jpg){kind=icon}
論文要旨 (199.6 kB)
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